As we age, our blood-brain barrier (BBB) becomes “leaky”—a challenge since this vital barrier protects our brain and maintains overall brain health.

But what if we could reinforce it?

Great news: we can! Exercise has been shown to positively affect the BBB. And the future holds even more promise with potential therapies targeting the BBB.

A ground breaking study from Chenghua Gu’s lab at Harvard is laying the foundation for the development of targeted therapeutics.

“This work serves as a foundation, revealing how alterations in cell interactions may control local blood vessel permeability and demonstrating the importance of performing both molecular and morphological characterizations to understand BBB properties.” https://lnkd.in/eRNh5um2.

At BrainKey, we’re advancing the measurement of BBB health using MRI imaging, allowing individuals to monitor changes and assess the impact of interventions.

For more information on the blood brain barrier see this review --> “The Blood-Brain Barrier: Composition, Properties, and Roles in Brain Health” https://lnkd.in/efZeeW5A

Exercise and the blood brain barrier --> “... exercise training may be effective in increasing the levels of neurotropic factors and reducing blood–brain barrier permeability in the elderly women” https://lnkd.in/e-Dzyc5S

The future of brain health is bright—and it starts with taking care of your BBB.